XTC may refer to:

• XTC, an English band
• "XTC" (Elgar), a 1930 song by Elgar
• XTC (album), a 1996 album by Anthony Hamilton
• Ivans XTC, a 2000 film directed by Bernard Rose
• MDMA, a drug with the street name "ecstasy", often abbreviated XTC
• XML Telemetric and Command Exchange (XTCE), an XML-based exchange format for spacecraft telemetry and command meta-data

This disambiguation page lists articles associated with the same title. If an internal link led you here, you may wish to change the link to point directly to the intended article.