Euthydemus may refer to:

• a ruler of the Greco-Bactrian Kingdom (3rd century BC); see Euthydemus I
• a son of Cephalus (5th/4th century BC); see Plato's Republic
• a dialogue by Plato; see Euthydemus (dialogue)
• a tyrant of Sicyon; see Euthydemus (tyrant)
• a fleetcommander for Athens during the Sicilian Expedition, 415 BC to 413 BC; see Euthydemus (commander)

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